| Identification | Back Directory | [Name]
Fmoc-NH-ethyl-SS-propionic acid | [CAS]
864235-83-6 | [Synonyms]
Fmoc-SS-linker
Fmoc-NH-ethyl-SS-propionic acid
3-[(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}ethyl)dithio]propanoicacid
3-((2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)disulfanyl)propanoic acid | [Molecular Formula]
C20H21NO4S2 | [MDL Number]
MFCD22380332 | [MOL File]
864235-83-6.mol | [Molecular Weight]
403.52 |
| Chemical Properties | Back Directory | [Melting point ]
104-106 °C | [Boiling point ]
634.5±45.0 °C(Predicted) | [density ]
1.330±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.25±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Fmoc-NH-ethyl-SS-propionic acid is a cleavable linker with acid to be reacted with amine-bearing molecules, The Fmoc protecting group can be removed under basic condition to obtain a free amine which can be used for further conjugations. | [Biological Activity]
Fmoc-NH-ethyl-SS-propionic acid is a cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs). | [in vitro]
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. | [target]
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