| Chemical Properties | Back Directory | [Boiling point ]
1775.9±65.0 °C(Predicted) | [density ]
1.425±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
2.98±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide. The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity[1]. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists[2]. | [storage]
Store at -20°C | [References]
[1]. US20120264685 [2]. US9738697 |
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| Company Name: |
Ontores Biotech
|
| Tel: |
0571-88760729 18072970094 |
| Website: |
www.ontoresinc.cn |
|