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86583-19-9

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86583-19-9 Structure

86583-19-9 Structure
IdentificationBack Directory
[Name]

3-Deazaadenosine (hydrochloride)
[CAS]

86583-19-9
[Synonyms]

3-Deazaadenosine (hydrochloride)
[Molecular Formula]

C11H15ClN4O4
[MOL File]

86583-19-9.mol
[Molecular Weight]

302.72
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
[form ]

A crystalline solid
Spectrum DetailBack Directory
[Spectrum Detail]

3-Deazaadenosine (hydrochloride)(86583-19-9)1HNMR
Hazard InformationBack Directory
[Biological Activity]

3-Deazaadenosine HCl (3-DZA, c3Ado) is a potent inhibitor of S-adenosylhomocysteine hydrolase with a Ki value of 3.9 μM.
[in vitro]

3-Deazaadenosine shows anti-HIV effect, and inhibits p24 antigen in peripheral blood mononuclear (PBMCs) cells infected with HIV-1 isolates (A012 and A018) with IC 50 s of 0.15 and 0.20 μM, respectively.
[target]

TargetValue
S-adenosylhomocysteine hydrolase
(Cell-free assay)		 3.9 μM(Ki)
[storage]

Store at -20°C
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