ChemicalBook--->CAS DataBase List--->869296-13-9

869296-13-9

869296-13-9 Structure

869296-13-9 Structure
IdentificationBack Directory
[Name]

T-26c
[CAS]

869296-13-9
[Synonyms]

T-26c
CPD1612
T-26c >=98% (HPLC)
Benzoic acid, 4-[[[1,4-dihydro-2-[[[(3-methoxyphenyl)methyl]amino]carbonyl]-4-oxothieno[2,3-d]pyrimidin-5-yl]methoxy]methyl]-
[Molecular Formula]

C24H21N3O6S
[MDL Number]

MFCD31558511
[MOL File]

869296-13-9.mol
[Molecular Weight]

479.51
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 10 mg/ml
[form ]

A crystalline solid
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Biological Activity]

T-26c is a highly potentselective and cell-permeable matrix metalloproteinases 13 (MMP-13) inhibitor. T-26c inhibits the breakdown of collagen (87.4% inhibition at 0.1 μM) in IL-1b and oncostatin M stimulated cartilage. For full characterization detailsplease visit the T-26c probe summary on the Structural Genomics Consortium (SGC) website.

To learn about other SGC chemical probes for protein targetsvisit sigma.com/sgc
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