ChemicalBook--->CAS DataBase List--->869886-67-9

869886-67-9

869886-67-9 Structure

869886-67-9 Structure
IdentificationBack Directory
[Name]

VRT752271
[CAS]

869886-67-9
[Synonyms]

CS-725
VRT752271
Padsevonil
Ulixertinib
VRT752271 HCl
BVD-523 ( VRT752271)
Ulixertinib (BVD-523)
Ulixertinib, VRT752271
VRT-752271(Ulixertinib)
Ulixertinib (BVD-523,VRT752271)
BVD-523, BVD 523, BVD523, VRT752271, VRT752271, VRT 752271, ULIXERTINIB
BVD-523; BVD 523; BVD523; ULIXERTINIB; VRT752271; VRT-752271; VRT 752271
(S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide
N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-4-[5-chloro-2-(propan-2-ylamino)pyridin-4-yl]-1H-pyrrole-2-carboxamide
4-(5-Chloro-2-isopropylamino-4-pyridinyl)pyrrole-2-carboxylic acid (S)-[1-(3-chlorophenyl)-2-hydroxyethyl]amide HCl
4-[5-Chloro-2-[(1-methylethyl)amino]-4-pyridinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide
1H-Pyrrole-2-carboxaMide, 4-[5-chloro-2-[(1-Methylethyl)aMino]-4-pyridinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-
4-[5-Chloro-2-[(1-methylethyl)amino]-4-pyridinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide VRT752271
[Molecular Formula]

C21H22Cl2N4O2
[MDL Number]

MFCD22628898
[MOL File]

869886-67-9.mol
[Molecular Weight]

433.33
Chemical PropertiesBack Directory
[Boiling point ]

682.8±55.0 °C(Predicted)
[density ]

1.359
[storage temp. ]

Store at -20°C
[solubility ]

DMSO:93.0(Max Conc. mg/mL);214.62(Max Conc. mM)
Ethanol:43.0(Max Conc. mg/mL);99.23(Max Conc. mM)
[form ]

Powder
[pka]

13.34±0.50(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[HS Code ]

2933998090
Hazard InformationBack Directory
[Uses]

Ulixertinib is a potent and reversible ERK1/ERK2 inhibitor with IC50 of <0.3 nM for ERK2. Inhibits cell proliferation. Anti-cancer.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

VRT752271(869886-67-9)1HNMR
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