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ChemicalBook--->CAS DataBase List--->874450-44-9

874450-44-9

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874450-44-9 Structure

874450-44-9 Structure
IdentificationBack Directory
[Name]

SEN 12333
[CAS]

874450-44-9
[Synonyms]

SEN 12333
WAY 317538
SEN 12333 WAY-317538
N-[4-(3-Pyridinyl)phenyl]-4-MorpholinepentanaMide
5-Morpholino-N-(4-(pyridin-3-yl)phenyl)pentanamide
4-MorpholinepentanaMide, N-[4-(3-pyridinyl)phenyl]-
[Molecular Formula]

C20H25N3O2
[MDL Number]

MFCD17167027
[MOL File]

874450-44-9.mol
[Molecular Weight]

339.43
Chemical PropertiesBack Directory
[storage temp. ]

Store at RT
[solubility ]

Soluble to 100 mM in DMSO
[form ]

Powder
[color ]

White to light yellow
Hazard InformationBack Directory
[Uses]

SEN 12333 is a nicotinic acetylcholine receptor (nAChR) agonist. SEN 12333 displays functional antagonism at histamine H3 receptors (IC50 = 103 nM) and weak agonist activity at human ganglionic α3 nAChRs (IC50 = 8.5 μM). Neuroprotective in a rodent model of quisqualic acid-induced cholinergic degeneration. SEN 12333 is a brain penetrant and orally bioavailable.
Spectrum DetailBack Directory
[Spectrum Detail]

SEN 12333(874450-44-9)1HNMR
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