| Identification | Back Directory | [Name]
safracin B | [CAS]
87578-99-2 | [Synonyms]
safracin B
2-Amino-N-[(6,7,9,10,13,14,14a,15-octahydro-1,7-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-10,13-dioxo-6,15-epimino-5H-isoquino[3,2-b][3]benzazocin-9-yl)methyl]propionamide
Propanamide, 2-amino-N-[[(6S,7S,9R,14aS,15R)-6,7,9,10,13,14,14a,15-octahydro-1,7-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-10,13-dioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-, (2S)- | [Molecular Formula]
C28H36N4O7 | [MDL Number]
MFCD01939882 | [MOL File]
87578-99-2.mol | [Molecular Weight]
540.61 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
Soluble in DMSO (up to 20 mg/ml) | [form ]
solid | [color ]
Yellow-green | [Stability:]
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| Hazard Information | Back Directory | [Description]
Safracin B (87578-99-2) is a novel antibiotic of the saframycin family produced by?Pseudomonas fluorescens.1?Safracin B displays antitumor activity against L1210 and P388 leukemias and B16 melanoma. Compared with safracin A, the toxic and effective doses were much lower. Safracin B also prolonged the life of tumor-bearing mice to a greater extent than safracin A.2 | [Uses]
Safracin B is a new antibiotics from the family of Safracin produced by Pseudomonas fluorescens A2-2. Safracin B is an antibiotic that exhibits anti-tumor properties. | [References]
1) Ikeda?et al.?(1983),?Safracins, new antitumor antibiotics. I. Producing organism, fermentation and isolation; J. Antibiot. Tokyo,?36?1279
2) Okumoto?et al. (1985),?Activity of safracins A and B, heterocyclic quinone antibiotics, on experimental tumors in mice; J. Antibiot.Tokyo,?38?767 |
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| Company Name: |
Fuxin Pharmaceutical
|
| Tel: |
021-50872116 13611907556 |
| Website: |
https://www.fuxinpharm.com |
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