| Identification | Back Directory | [Name]
DELTA12-PROSTAGLANDIN J2 | [CAS]
87893-54-7 | [Synonyms]
C05958
Δ12-PGJ2
DELTA12-PGJ2
12-PROSTAGLANDIN J2
Δ12-Prostaglandin J2
DELTA12-PROSTAGLANDIN J2
TUXFWOHFPFBNEJ-GJGHEGAFSA-N
Δ12-PGJ2 (Δ12-Prostaglandin J2)
Delta12-PGJ2 (Delta12-Prostaglandin J2)
13,14-dihydro-Delta(12)-prostaglandin J2
Δ12-Prostaglandin J2 Lipid Maps MS Standard
11-OXO-15S-HYDROXY-PROSTA-5Z,9,12E-TRIEN-1-OIC ACID
(5Z,12E,15S)-15-Hydroxy-11-oxoprosta-5,9,12-trien-1-oic acid
(5Z,12E,15S)-11-Oxo-15-hydroxyprosta-5,9,12-triene-1-oic acid
Prosta-5,9,12-trien-1-oic acid, 15-hydroxy-11-oxo-, (5Z,12E,15S)-
9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2
(Z)-7-[(1S,5E)-5-[(3S)-3-hydroxyoctylidene]-4-oxo-1-cyclopent-2-enyl]hept-5-enoic acid | [Molecular Formula]
C20H30O4 | [MDL Number]
MFCD00065805 | [MOL File]
87893-54-7.mol | [Molecular Weight]
334.45 |
| Chemical Properties | Back Directory | [Boiling point ]
531.2±50.0 °C(Predicted) | [density ]
1.111±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-d12, | [form ]
Liquid | [pka]
4.75±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
Δ12-PGJ2 is a decomposition product of PGD2 in aqueous media in the presence of albumin. It has antitumor and antiviral activity, inhibiting growth of cultured L1210 cells at with an IC50 value of 0.7 μg/ml. Δ12-PGJ2 is present in normal human urine with a 24 hour excretion rate of 50-150 ng. It is also a moderately potent PPARγ ligand. | [Uses]
delta12-PGJ2 (delta12-Prostaglandin J2) is a decomposition product of PGD2 showing potent antiviral and anti-proliferative activity. | [Uses]
Δ12-PGJ2 is a decomposition product of PGD2 in aqueous media in the presence of albumin. It has antitumor and antiviral activity, inhibiting growth of cultured L1210 cells at with an IC50 value of 0.7 μg/ml. Δ12-PGJ2 is present in normal human urine with a 24 hour excretion rate of 50-150 ng. It is also a moderately potent PPARγ ligand. | [Definition]
ChEBI: 13,14-dihydro-Delta(12)-prostaglandin J2 is a member of the class of prostaglandins J that is prosta-5,9,12-trien-1-oic acid carrying oxo and hydsroxy substituents at positions 11 and 15 respectively (the 5Z,12E,15S-stereoisomer). It has a role as an antineoplastic agent and an antiviral agent. It is a prostaglandins J and a secondary alcohol. It is functionally related to a prostaglandin J2. It is a conjugate acid of a 13,14-dihydro-Delta(12)-prostaglandin J2(1-). | [storage]
Store at -20°C |
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