| Identification | Back Directory | [Name]
L-Leucinamide, N-[(5-methyl-3-isoxazolyl)carbonyl]-L-al | [CAS]
884650-98-0 | [Synonyms]
MPro N3,MPro N-3
L-Leucinamide, N-[(5-methyl-3-isoxazolyl)carbonyl]-L-al
L-Leucinamide, N-[(5-methyl-3-isoxazolyl)carbonyl]-L-alanyl-L-valyl-N-[(1S,2E)-4-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]-4-(phenylmethoxy)-2-buten-1-yl]- | [Molecular Formula]
C35H48N6O8 | [MOL File]
884650-98-0.mol | [Molecular Weight]
680.79 |
| Chemical Properties | Back Directory | [Boiling point ]
990.8±65.0 °C(Predicted) | [density ]
1.192±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO|34.04|50| | [form ]
Solid | [pka]
12.42±0.46(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Definition]
ChEBI: N-[(5-methyl-1,2-oxazol-3-yl)carbonyl]-L-alanyl-L-valyl-N-{(2S,3E)-5-(benzyloxy)-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pent-3-en-2-yl}-L-leucinamide is a tripeptide resulting from the formal condensation of the carboxy group of N-[(5-methyl-1,2-oxazol-3-yl)carbonyl]-L-alanyl-L-valine with the amino group of benzyl (2E,4S)-4-(L-leucylamino)-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate. It is an inhibitor of the main protease of SARS-CoV-2. It has a role as an antiviral agent, an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor and an anticoronaviral agent. It is a tripeptide, a member of isoxazoles, a member of pyrrolidin-2-ones and a benzyl ester. | [storage]
Store at -20°C |
|
|