| Identification | Back Directory | [Name]
11-Hydroxy-sugiol | [CAS]
88664-08-8 | [Synonyms]
11-hydroxy-sugio
11-Hydroxy-sugiol
11-Hydroxylsugiol
Demethylcryptojaponol
12-O-deMethylcryptojapanol
11,12-dihydroxyabieta-8,11,13-trien-7-one
9(1H)-Phenanthrenone, 2,3,4,4a,10,10a-hexahydro-5,6-dihydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aS,10aS)- | [Molecular Formula]
C20H28O3 | [MDL Number]
MFCD28964223 | [MOL File]
88664-08-8.mol | [Molecular Weight]
316.43 |
| Chemical Properties | Back Directory | [Melting point ]
192-194℃ | [Boiling point ]
482.2±45.0 °C(Predicted) | [density ]
1.110±0.06 g/cm3 (20 ºC 760 Torr) | [pka]
8.55±0.60(Predicted) |
| Hazard Information | Back Directory | [Definition]
ChEBI: 11-hydroxysugiol is an abietane diterpenoid that is sugiol in which the hydrogen ortho to the phenolic hydroxy group has been replaced by a hydroxy group. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an EC 3.1.1.8 (cholinesterase) inhibitor and a plant metabolite. It is an abietane diterpenoid, a carbotricyclic compound, a meroterpenoid, a cyclic terpene ketone and a member of catechols. It is functionally related to a ferruginol and a sugiol. | [Cytotoxicity]
IC50 (μg/mL): 1.2 (A2780) (Topcu et al.2008) |
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