ChemicalBook--->CAS DataBase List--->89213-87-6

89213-87-6

89213-87-6 Structure

89213-87-6 Structure
IdentificationBack Directory
[Name]

ANP 1-28, HUMAN
[CAS]

89213-87-6
[Synonyms]

HANF
α-hANP
Carperitide
ANP 1-28, HUMAN
ANF 1-28, HUMAN
ANP HUMAN, 1-28
ahANF, Carperitide
ANP, ALPHA-, HUMAN
Carperitide Acetate
α-Atriopeptin【human】
Carperitide impurity
ALPHA-ANF (1-28), HUMAN
ANP 1-28, HUMAN USP/EP/BP
ANF (1-28), HUMAN, PORCINE
SLRRSSCFGGRMDRIGAQSGLGCNSFRY
[MET(O)12]-ANP (HUMAN, 1-28)
Carperitide(ANP(1-28)/human)
ALPHA-ANP [1-28] HUMAN, CANINE
Atrial natriuretic factor【human】
ATRIAL NATRIURETIC PEPTIDE HUMAN
Carperitide Acetate, carperitida
Carperitide / Carperitide Acetate
atrial natriuretic factor (99-126)
Atrial natriuretic peptide【porcine】
ATRIAL NATRIURETIC FACTOR 1-28, HUMAN
ATRIAL NATRIURETIC PEPTIDE HUMAN, 1-28
ATRIAL NATRIURETIC PEPTIDE 1-28, HUMAN
ALPHA-ATRIAL NATRIURETIC PEPTIDE, HUMAN
ATRIAL NATRIURETIC PEPTIDE, ALPHA-, HUMAN
Atrial natriureticpeptide-28 (huMan) (9CI)
ANP (HUMAN, 1-28) (PORCINE, BOVINE, CANINE)
ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, CANINE)
ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, PORCINE)
ATRIAL NATRIURETIC PEPTIDE (1-28), HUMAN, PORCINE
ALPHA-ATRIAL NATRIURETIC PEPTIDE, HUMAN, RECOMBINANT
SLRRSSCFGGRMDRIGAQSGLGCNSFRY (DISULFIDE BRIDGE: 7-23)
Atrial Natriuretic Factor (1-28) (huMan) αhANF, Carperitide
[MET(O)12]-A-TYPE (ATRIAL) NATRIURETIC PEPTIDE (HUMAN, 1-28)
Atrial Natriuretic Factor (1-28) (human), αhANF, Carperitide
Atrial Natriuretic Peptide (1-28) (human) (trifluoroacetate salt)
A-TYPE (ATRIAL) NATRIURETIC PEPTIDE (HUMAN, 1-28) (PORCINE, BOVINE, CANINE)
SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR
SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET(O)-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR
H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH
H-SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR-OH (DISULFIDE BRIDGE: 7-23)
SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET: O-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR[SLRRSSCFGGR-MET: O-DRIGAQSGLGCNSFRY]DISULFIDE BRIDGE CYS7-CYS23.
Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond)
L-Tyrosine, L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-, cyclic (7→23)-disulfi...
[EINECS(EC#)]

686-482-9
[Molecular Formula]

C127H203N45O39S3
[MDL Number]

MFCD00076226
[MOL File]

89213-87-6.mol
[Molecular Weight]

3080.44
Chemical PropertiesBack Directory
[density ]

1.55±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Water: 1 mg/ml
[form ]

A lyophilized powder
[Sequence]

H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH,(Disulfide bridge: Cys-Cys)
[InChIKey]

NSQLIUXCMFBZME-VUEHYBQXNA-N
Safety DataBack Directory
[Symbol(GHS) ]


GHS08
[Signal word ]

Warning
[Hazard statements ]

H361
[Precautionary statements ]

P201-P202-P281-P308+P313-P405-P501
Hazard InformationBack Directory
[Description]

Carperitide is the α-human atrial natriuretic peptide (α-hANP) produced by recombinant technology. It was introduced in Japan as a treatment for acute congestive heart failure (CHF). In dogs with CHF, carperitide significantly reduced the elevated left ventricular end-diastolic pressure and the index of myocardial oxygen consumption (systolic blood pressure x heart rate). In a clinical trial, carperitide was effective in improving hemodynamics and symptoms in 60% of patients with acute CHF. Carperitide was reported to be well tolerated with no significant adverse effects clinically. A beneficial effect on hemodynamics has been reported in chronic heart failure patients. Carperitide is also in clinical trials for maintenance of blood pressure during surgical operations.
[Originator]

Suntory (Japan)
[Uses]

Treatment of decompensated congestive heart failure.
[Definition]

ChEBI: Carperitide is a polypeptide.
[Brand name]

Daiichi Suntory, Japan.
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