| Identification | Back Directory | [Name]
9BETA,11ALPHA,15S-TRIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, TRIS (HYDROXYMETHYL)AMINOMETHANE SALT | [CAS]
89847-02-9 | [Synonyms]
9BETA-PGF2ALPHA (TROMETHAMINE SALT)
Prostaglandin F2β (tromethamine salt)
PROSTAGLANDIN F2BETA TROMETHAMINE SALT
9BETA,11ALPHA,15S-TRIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, TRIS (HYDROXYMETHYL)AMINOMETHANE SALT
2-amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5R)-3,5-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)hept-5-enoate | [Molecular Formula]
C24H45NO8 | [MDL Number]
MFCD00135236 | [MOL File]
89847-02-9.mol | [Molecular Weight]
475.62 |
| Chemical Properties | Back Directory | [solubility ]
Acetone: >5 mg/ml (from PGF2a THAM); Acetonitrile: >5 mg/ml (from PGF2a THAM); DMSO: >50 mg/ml (from PGF2a THAM); Ethanol: >50 mg/ml (from PGF2a THAM); Methanol: >100 mg/ml (from PGF2a THAM); PBS pH 7.2: >25 mg/ml (from PGF2a THAM) | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Description]
Prostaglandin F2β (PGF2β) (tromethamine salt) is a derivative of PGF2β with increased water solubility. PGF2β is the 9β-hydroxy stereoisomer of PGF2α . It is much less active than PGF2α in antifertility and bronchoconstrictor activities. PGF2β exhibits bronchodilating activity in guinea pigs and cats and antagonizes the bronchoconstrictor activity of PGF2α. |
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