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905585-60-6

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905585-60-6 Structure

905585-60-6 Structure
IdentificationBack Directory
[Name]

3-Pyridinecarbonitrile, 5-fluoro-2-[[(1S)-1-(4-fluorophenyl)ethyl]amino]-6-[[5-(1-methylethoxy)-1H-pyrazol-3-yl]amino]-
[CAS]

905585-60-6
[Synonyms]

3-Pyridinecarbonitrile, 5-fluoro-2-[[(1S)-1-(4-fluorophenyl)ethyl]amino]-6-[[5-(1-methylethoxy)-1H-pyrazol-3-yl]amino]-
[Molecular Formula]

C20H20F2N6O
[MOL File]

905585-60-6.mol
[Molecular Weight]

398.41
Hazard InformationBack Directory
[Description]

AZD6918 is a novel potent and selective inhibitor of the Trk tyrosine kinases. AZD-6918 attenuates the BDNF/TrkB-induced protection of neuroblastoma cells from etoposide in vitro and in vivo. AZD6918 inhibited wild-type TrkB-induced cell migration and cell growth.
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