| Identification | Back Directory | [Name]
Crisaborole Impurity | [CAS]
906673-42-5 | [Synonyms]
Crisaborole Impurity 26
Crisaborole intermediate
5-(4-cyanophenoxy)-2-hydroxybenzoic acid
4-(3-formyl-4-hydroxyphenoxy)benzonitrile
4-(2-bromo-5-(hydroxymethyl)phenoxy)benzonitrile
4-(2,4-dibromo-5-(hydroxymethyl)phenoxy)benzonitrile
4-(4-(4-bromo-3-formylphenoxy)-3-formylphenoxy)benzonitrile
3-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]Benzonitrile
3-[(1-Hydroxy-1 3-dihydro-2
1-benzoxaborole-5-yl)oxy]benzonitrile
Benzonitrile, 3-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
4-(4-(4-bromo-3-(hydroxymethyl)phenoxy)-3-(hydroxymethyl)phenoxy)benzonitrile
4-((2,2'-diformyl-4'-(4-isocyanophenoxy)-[1,1'-biphenyl]-4-yl)oxy)benzonitrile
4-(3-(hydroxymethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)benzonitrile
4-(4-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)-3-(hydroxymethyl)phenoxy)benzonitrile
4-(3-formyl-4-(3-formyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)phenoxy)benzonitrile | [Molecular Formula]
C14H10BNO3 | [MDL Number]
MFCD22415398 | [MOL File]
906673-42-5.mol | [Molecular Weight]
251.05 |
| Chemical Properties | Back Directory | [Melting point ]
180-183°C | [Boiling point ]
411.1±55.0 °C(Predicted) | [density ]
1.33±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
7.04±0.20(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
5-(4-Cyanophenoxy)-2-hydroxybenzoic Acid is an impurity of Crisaborole(H947928). Crisaborole exhibits inhibitory activity against PDE4 and cytokine release. |
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