| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: slightly; PBS (pH 7.2): 5 mg/ml | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Description]
Motilin is a polypeptide hormone that stimulates gastric motility through release in the small intestine and into the general circulation during fasting. In isolated rabbit duodenal segments, porcine motilin (10 nM-1 μM) induced phasic contractions and acetylcholine release from enteric neurons (EC50 = 2.5 nM). Formulations containing motilin are used to increase gastrointestinal motility in patients with diabetic gastroparesis, often in combination with erythromycin , an antibiotic and agonist at the motilin receptor. |
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