| Identification | Back Directory | [Name]
1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYL-N-METHYL-PYRROLIDINIUM ETHANOL | [CAS]
91021-63-5 | [Synonyms]
PYRROLIDINO PAF C-16
QBLLCUIJMABRFJ-MUUNZHRXSA-N
1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYL-N-METHYL-PYRROLIDINIUM ETHANOL | [Molecular Formula]
C28H56NO7P | [MDL Number]
MFCD00216142 | [MOL File]
91021-63-5.mol | [Molecular Weight]
549.72 |
| Hazard Information | Back Directory | [Description]
Pyrrolidino PAF C-16 is a synthetic analog of PAF C-16. It is a potent mediator of PAF-like activities, including hypotension and platelet aggregation, where it is approximately 3-10 times more potent than PAF itself. | [Definition]
ChEBI: Pyrrolidinium, 1-[(7r)-7-(acetyloxy)-4-hydroxy-4-oxido-3,5,9-trioxa-4-phosphapentacos-1-yl]-1-methyl-, inner salt is a glycerophospholipid. | [References]
[1]. shigenobu k, masuda y, tanaka y, et al. platelet activating factor analogues: lack of correlation between their activities to produce hypotension and endothelium-mediated vasodilation. j pharmacobiodyn. 1985 feb;8(2):128-33.
[2]. kasuya y, masuda y, shigenobu k. hypotensive actions of some analogues of platelet-activating factor (paf) with higher potencies than natural paf. can j physiol pharmacol. 1984 apr;62(4):457-9. |
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