| Identification | Back Directory | [Name]
Caffeine Citrate | [CAS]
93390-81-9 | [Synonyms]
XWLUWCNOOVRFPX-UHFFFAOYSA-N
2,4-Imidazolidinedione, 5,5-diphenyl-3-[(phosphonooxy)methyl]- | [Molecular Formula]
C16H15N2O6P | [MOL File]
93390-81-9.mol | [Molecular Weight]
362.27 |
| Hazard Information | Back Directory | [Description]
Cerebyx was launched for the treatment of status epilepticus and
for neurosurgery derived seizures. Fosphenytoin is rapidly converted by
phosphatases to phenytoin. This compound is readily water soluble thus overcoming
an important problem associated with Dilantin. | [Originator]
Warner-Lambert (USA) | [Uses]
Anticonvulsant. | [Definition]
ChEBI: Fosphenytoin is an imidazolidine-2,4-dione. | [Manufacturing Process]
By action of formaldehyde and hydrochloric acid on 5,5-diphenylhydantoin was
prepared 3-hydroxymethyl-5,5-diphenyl-imidazolidine-2,4-dione which was
converted by action PCl3 to 3-chloromethyl-5,5-diphenyl-imidazolidine-2,4-
dione by action PCl3. Then the chlorine atom was substituted on P(O)(OBz)Ogroup by action of argentum salt of phosphoric acid dibenzyl ester. Removal of
the protecting groups by hydrogenolysis gives the 2,4-imidazolidinedione, 5,5-
diphenyl-3-((phosphonooxy)methyl)- (fosphenytoin).
In practice it is usually used as sodium salt. | [Brand name]
Cerebyx (Parke-Davis). | [Therapeutic Function]
Antiepileptic, Anticonvulsant |
|
| Company Name: |
Leancare Ltd.
|
| Tel: |
+33 962096793 |
| Website: |
www.leancare.co.uk |
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