ChemicalBook--->CAS DataBase List--->937812-80-1

937812-80-1

937812-80-1 Structure

937812-80-1 Structure
IdentificationBack Directory
[Name]

(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one
[CAS]

937812-80-1
[Synonyms]

HYR-141
Otamixaban
SynonyMs: HYR-141
γ-Secretase Modulators
γ-Secretase Modulators
gaMMa-Secretase Modulators
AMyloid-β production inhibitor
Amyloid-β production inhibitor
gammaSecretase Modulators,gamma Secretase Modulators
(E)-(4R,9AS)-7-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)h
(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one
hexahydro-7-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-4-(3,4,5-trifluorophenyl)-(4R,7E,9aS)-Pyrido[2,1-c][1,4]oxazin-6(1H)-one
Pyrido[2,1-c][1,4]oxazin-6(1H)-one, hexahydro-7-[[3-Methoxy-4-(4-Methyl-1H-iMidazol-1-yl)phenyl]Methylene]-4-(3,4,5-trifluorophenyl)-, (4R,7E,9aS)-
[Molecular Formula]

C26H24F3N3O3
[MDL Number]

MFCD13184813
[MOL File]

937812-80-1.mol
[Molecular Weight]

483.48
Chemical PropertiesBack Directory
[Boiling point ]

682.5±55.0 °C(Predicted)
[density ]

1.37
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Powder
[pka]

5.76±0.61(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

A potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. Clinical studies show that it is efficacious, safe and well tolerated in humans and therefore has considerable potential for the treatment of acute coronary syndrome.
[storage]

Store at -20°C
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