ChemicalBook--->CAS DataBase List--->939431-68-2

939431-68-2

939431-68-2 Structure

939431-68-2 Structure
IdentificationBack Directory
[Name]

4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile
[CAS]

939431-68-2
[Synonyms]

Etravirine Impurity 12
4-[[6-amino-2-(4-cyanoanilino)-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile
4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile
4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile
Benzonitrile, 4-[[6-amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-
[EINECS(EC#)]

458-850-7
[Molecular Formula]

C20H16N6O
[MDL Number]

MFCD17012694
[MOL File]

939431-68-2.mol
[Molecular Weight]

356.38
Chemical PropertiesBack Directory
[Melting point ]

284.5-287 °C
[Boiling point ]

632.1±65.0 °C
Hazard InformationBack Directory
[Uses]

4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile is an impurity of Etravirine (E937000), which is a novel HIV reverse transcriptase inhibitor useful in treatment of HIV infection. It can be used as a novel HIV-1 NNRTIs by using its hydrophobic channel and tolerant regions of NNIBP. It can also be used to synthesize etravirine, a non-nucleoside reverse transcriptase inhibitor.
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