| Identification | Back Directory | [Name]
Mycro3 | [CAS]
944547-46-0 | [Synonyms]
Mycro3
Mycro-3, >98%
ethyl 5-[[7-[chloro(difluoro)methyl]-5-(furan-2-yl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]amino]-1-phenylpyrazole-4-carboxylate
1H-Pyrazole-4-carboxylic acid, 5-[[[7-(chlorodifluoromethyl)-5-(2-furanyl)pyrazolo[1,5-a]pyrimidin-2-yl]carbonyl]amino]-1-phenyl-, ethyl ester | [Molecular Formula]
C24H17ClF2N6O4 | [MDL Number]
MFCD03409284 | [MOL File]
944547-46-0.mol | [Molecular Weight]
526.88 |
| Chemical Properties | Back Directory | [density ]
1.53±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [solubility ]
DMSO : ≥ 100 mg/mL (189.80 mM) | [form ]
Solid | [pka]
6.95±0.46(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Biological Activity]
Mycro 3 is a potent selective Myc-Max dimerization inhibitor. It can be used in pancreatic cancer research. | [in vitro]
Mycro 3 is a potent and selective c-Myc inhibitor in whole cell assays, with weak inhibitory activity against Activator protein 1 (AP-1). It has a superior specificity profile to its predecessors. It inhibits the interaction between c-Myc and Max. It has high selectivity and inhibits c-Myc/Max dimerization and conjugation with DNA. | [target]
| [storage]
Store at -20°C |
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