ChemicalBook--->CAS DataBase List--->944561-44-8

944561-44-8

944561-44-8 Structure

944561-44-8 Structure
IdentificationBack Directory
[Name]

H2N-PEG2-Propyne
[CAS]

944561-44-8
[Synonyms]

944561-44-8
Alkyne-PEG2-NH2
H2N-PEG2-Propyne
HC≡C-CH2-PEG2-NH2
Alkyne-PEG2-amine
Propargyl-PEG2-NH2
Propyne-PEG2-amine
Propargyl-PEG2-amine
2-(2-prop-2-ynoxyethoxy)ethanamine
2-(2-Prop-2-ynyloxy-ethoxy)-ethyla
2-[2-(Propargyloxy)ethoxy]ethylamine
2-[2-(2-Propynyloxy)ethoxy]ethylamine
2-[2-(2-Propynyloxy)ethoxy]ethylamine>
2-(2-(prop-2-yn-1-yloxy)ethoxy)ethanamine
Ethanamine, 2-[2-(2-propyn-1-yloxy)ethoxy]-
2-(2-(prop-2-yn-1-yloxy)ethoxy)ethan-1-amine
2-(2-(prop-2-yn-1-yloxy)ethoxy)ethan-1-amine hydrochloride
[Molecular Formula]

C7H13NO2
[MDL Number]

MFCD19160595
[MOL File]

944561-44-8.mol
[Molecular Weight]

143.184
Chemical PropertiesBack Directory
[Boiling point ]

213.8±20.0 °C(Predicted)
[density ]

0.992±0.06 g/cm3(Predicted)
[refractive index ]

1.4590 to 1.4630
[storage temp. ]

under inert gas (nitrogen or Argon) at 2–8 °C
[solubility ]

DMSO:100.0(Max Conc. mg/mL);698.37(Max Conc. mM)
[form ]

clear liquid
[pka]

8.72±0.10(Predicted)
[color ]

Colorless to Almost colorless
Safety DataBack Directory
[RIDADR ]

UN 2735 8/PG II
[HS Code ]

2922.19.9690
[HazardClass ]

8
[PackingGroup ]

II
Hazard InformationBack Directory
[Description]

Propargyl-PEG2-amine is a crosslinker that is reactive with NHS esters, carbonyls (carboxylic acid, ketone, aldehyde). The propargyl group can participate in copper catalyzed azide-alkyne Click Chemistry reaction to form a stable triazole linkage.
[Uses]

2-[2-(2-Propynyloxy)ethoxy]ethylamine is used in preparation of RSV F protein inhibitors conjugated to Fc variants and albumins.
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