Identification | Back Directory | [Name]
16-phenoxy Prostaglandin F2α ethyl amide | [CAS]
951319-59-8 | [Synonyms]
16-phenoxy PGF2α ethyl amide 16-phenoxy Prostaglandin F2α ethyl amide 16-phenoxy Prostaglandin F2α ethyl amide 16-phenoxy Prostaglandin F2.alpha. ethyl amide (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-phenoxybut-1-enyl)cyclopentyl)-N-ethylhept-5-enamide (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]cyclopentyl]-N-ethylhept-5-enamide 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]cyclopentyl]-N-ethyl-, (5Z)- | [Molecular Formula]
C24H35NO5 | [MDL Number]
MFCD22380627 | [MOL File]
951319-59-8.mol | [Molecular Weight]
417.54 |
Hazard Information | Back Directory | [Description]
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α. Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid. |
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