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951319-59-8

951319-59-8 Structure

951319-59-8 Structure
IdentificationBack Directory
[Name]

16-phenoxy Prostaglandin F2α ethyl amide
[CAS]

951319-59-8
[Synonyms]

16-phenoxy PGF2α ethyl amide
16-phenoxy Prostaglandin F2α ethyl amide
16-phenoxy Prostaglandin F2α ethyl amide
16-phenoxy Prostaglandin F2.alpha. ethyl amide
(Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-phenoxybut-1-enyl)cyclopentyl)-N-ethylhept-5-enamide
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]cyclopentyl]-N-ethyl-, (5Z)-
[Molecular Formula]

C24H35NO5
[MDL Number]

MFCD22380627
[MOL File]

951319-59-8.mol
[Molecular Weight]

417.54
Chemical PropertiesBack Directory
[solubility ]

DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 1 mg/ml
[form ]

A crystalline solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H302-H360
[Precautionary statements ]

P201-P202-P264-P270-P280-P301+P312-P330-P308+P313-P405-P501
Hazard InformationBack Directory
[Description]

Prostaglandin F (PGF), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 16-phenoxy PGF is a metabolically stable analog of PGF. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF. Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.
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