ChemicalBook--->CAS DataBase List--->95851-37-9

95851-37-9

95851-37-9 Structure

95851-37-9 Structure
IdentificationBack Directory
[Name]

kadsurenone
[CAS]

95851-37-9
[Synonyms]

kadsurenone
(2S)-2α-(3,4-Dimethoxyphenyl)-3,3a-dihydro-3aα-methoxy-3β-methyl-5-(2-propenyl)-6(2H)-benzofuranone
6(2H)-Benzofuranone, 2-(3,4-dimethoxyphenyl)-3,3A-dihydro-3A-methoxy-3-methyl-5-(2-propenyl)-, (2S-(2alpha,3beta,3aalpha))-
[Molecular Formula]

C21H24O5
[MDL Number]

MFCD00869351
[MOL File]

95851-37-9.mol
[Molecular Weight]

356.416
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
[LogP]

2.870 (est)
Hazard InformationBack Directory
[Uses]

Kadsurenone acts as a platelet activating factor (PAF) receptor antagonist. PAF is an important mediator of endotoxin-induced hypotension in rats.
[Definition]

ChEBI: Kadsurenone is a member of benzofurans.
[in vivo]

Kadsurenone (i.v.; 20 and 30 mg/kg) undergoes hepatobiliary excretion but might not be regulated by P-glycoprotein (P-gp) transported system[1].

Animal Model:Sprague-Dawley rats[1]
Dosage:0 and 30 mg/kg
Administration:IV
Result:Could go through hepatobiliary excretion.
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