| Identification | Back Directory | [Name]
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxy-ethyl]acetamide | [CAS]
97476-58-9 | [Synonyms]
Midodrine Hydrochloride Intermediates
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxy-ethyl]acetamide | [Molecular Formula]
C12H18N2O4 | [MOL File]
97476-58-9.mol |
| Hazard Information | Back Directory | [Definition]
ChEBI: Midodrine is an aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine. It has a role as a prodrug, an alpha-adrenergic agonist, a sympathomimetic agent and a vasoconstrictor agent. It is a secondary alcohol, an amino acid amide and an aromatic ether. It is functionally related to a glycinamide and a deglymidodrine. It is a conjugate base of a midodrine(1+). |
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