| Identification | Back Directory | [Name]
(N-piperidinomethyl)-2-chroman | [CAS]
99290-94-5 | [Synonyms]
Reaxys ID: 5747013
(N-piperidinomethyl)-2-chroman
Piperidine, 1-[(3,4-dihydro-2H-1-benzopyran-2-yl)methyl]- | [Molecular Formula]
C15H21NO | [MOL File]
99290-94-5.mol | [Molecular Weight]
231.33 |
| Hazard Information | Back Directory | [Description]
The alpha-adrenoceptors blocking effect of (N-piperidinomethyl)-2-chromanne was studied in vivo and in vitro in the rat. In the pithed rat, (N-piperidinomethyl)-2-chromanne (1 mg/kg i.v.) antagonized the pressor effects induced by alpha agonists. (N-piperidinomethyl)-2-chromanne competitively antagonized the pressor effects of M7 (alpha 2-agonist) and cirazoline (alpha 1-agonist). (N-piperidinomethyl)-2-chromanne antagonized the inhibitory effects of clonidine on presynaptic alpha 2-receptors in stimulated pithed rats. |
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