| Identification | Back Directory | [Name]
8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE | [CAS]
99295-33-7 | [Synonyms]
159021
SKF 83566 HYDROBROMIDE
(+/-)-SKF-83566 HYDROCHLORIDE SELECTIVE DOPAMINE D1
8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol
1H-3-Benzazepin-7-ol, 8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-
8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE
(±)-SCH-24543, (±)-7-Bromo-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C17H18BrNO | [MDL Number]
MFCD04039787 | [MOL File]
99295-33-7.mol | [Molecular Weight]
332.23 |
| Hazard Information | Back Directory | [Uses]
SKF 83566 Hydrobromide is a very potent and selective D1-like dopamine receptor antagonist, specifically at the 5-HT2 receptor. | [Definition]
ChEBI: 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol is a benzazepine. | [Biological Activity]
Potent and selective D 1 -like dopamine receptor antagonist (K i ~ 0.56 nM for D 1 ; K B = 2 μ M for D 2 ). Also antagonist at the vascular 5-HT 2 receptor (K i = 11 nM). Centrally active following systemic administration in vivo . |
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