1015167-40-4
中文名称
达比加群酰基Β维葡糖苷酸
英文名称
Dabigatran Acyl-β-D-Glucuronide
CAS
1015167-40-4
分子式
C31H33N7O9
分子量
647.635
MOL 文件
1015167-40-4.mol
1015167-40-4 结构式
基本信息
中文别名
达比加群代谢物达比加群酰基Β维葡糖苷酸
达比加群酰基-D-葡萄糖醛酸
达比加群酰基-?-D-葡糖苷酸TFA盐
达比加群酯酰基-?-D-葡糖苷酸三氟乙酸盐
达比加群酰基-?-D-葡糖苷酸-D3 TFA盐
达比加群酰基--?-D-葡萄糖醛酸 三氟乙酸盐
达比加群酰基--?-D-葡萄糖醛酸-D3 三氟乙酸盐
N-[[2-[[[4-(氨基亚胺甲基)苯基]氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]羰基]-N-2-吡啶基-BETA-丙氨酸 BETA-D-吡喃葡糖酸基酯
英文别名
Dabigatran Acyl GlucuronideDabigatran Acyl-β-D-Glucuronide
Dabigatran Acyl-β-D-Glucuronide
Dabigatran β-Acyl Glucuronide D4
Dabigatran Acyl-Beta-D-Glucuronide
Dabigatran Acyl-?-D-Glucuronide TFA Salt
Dabigatran Acyl-?-D-Glucuronide-D3 TFA Salt
Dabigatran Acyl--D- glucuronide trifluroacetic acid
Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt
Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt (80%)
物理化学性质
熔点>155°C (dec.)
储存条件Hygroscopic, -20°C Freezer, Under Inert Atmosphere
溶解度可溶于DMSO（微溶）、甲醇（微溶、加热）、水
形态固体
颜色灰白色至浅棕色
稳定性吸湿性，溶液不稳定
应用领域
用途1
The major metabolite of Dabigatran (D100090) in humans. Four isomeric acylglucuronides of Dabigatran were isolated and purified from urine of dosed rhesus monkeys. NMR analysis confirmed the structur es of the four metabolites as the 1-O-acylglucuronide (β anomer) and the 2-O-, 3-O-, and 4-O-acylglucuronides (α and β anomers).