101708-64-9

中文名称化合物 T28311

英文名称 PD 116152

CAS 101708-64-9

分子式 C16H12N2O6

分子量 328.28

MOL 文件 101708-64-9.mol

101708-64-9 结构式

基本信息应用领域

基本信息

中文别名

化合物 T28311
抗生素 PD 116152

英文别名

PD 116152
Antibiotic PD-116152
6-Formyl-4,7,9-trihydroxy-8-methylphenazine-1-carboxylic acid methyl ester
6-Formyl-4,7,9-trihydroxy-8-methyl-1-phenazinecarboxylic acid methyl ester
1-Phenazinecarboxylic acid, 6-formyl-4,7,9-trihydroxy-8-methyl-, methyl ester

应用领域

用途一

PD 116152 is a new, highly substituted phenazine with antitumor activity was isolated from the culture broth of a Streptomyces sp. It is a novel phenazine antitumor antibiotic. The antibiotic is selectively active versus the bacterium Streptococcus pneumoniae (MIC less than 0.46 microgram/ml); the antitumor activity versus murine P388 leukemia is T/C 149.