1031367-64-2
1031367-64-2 结构式
物理化学性质
沸点536.6±50.0 °C(Predicted)
密度1.183±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度可溶于DMSO
酸度系数(pKa)9.80±0.26(Predicted)
形态结晶固体
颜色White to off-white
应用领域
用途一
MC-70 is a potent P-gp inhibitor (EC50 = 0.69 μM). Multidrug resistance (MDR) is the major cause of the failure of cancer therapy since this phenomenon generates cancer cells that are unresponsive to chemotherapeutic agents. P-glycoprotein (P-gp) is a well-known membrane transporter expressed in a number of strategic biological barriers, where it exerts a protective effect of paramount importance.