10376-48-4
中文名称
紫菀酮
英文名称
SHIONONE
CAS
10376-48-4
分子式
C30H50O
分子量
426.72
MOL 文件
10376-48-4.mol
更新日期
2025/01/10 09:25:19
10376-48-4 结构式
基本信息
中文别名
紫菀酮紫苑酮
紫菀酮 20MG
紫苑酮(紫菀酮)
紫菀酮, 来源于紫菀
S-HIONONE 紫菀酮
英文别名
ShiononSHIONONE
Shionone ,98%
21-Shionen-3-one
18,19-Seco-D:A-friedolup-19-en-3-one
Shionone, 98%, from Aster tataricus L. f.
2(1H)-Chrysenone,hexadecahydro-1,4b,6a,8,10a,12a-
hexamethyl-8-(4-methyl-3-pentenyl)-,(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-
3β,5,8,17aβ-Tetramethyl-3-(4-methyl-3-pentenyl)-D-homo-5α-androstan-17-one
2(1H)-Chrysenone, hexadecahydro-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methyl-3-penten-1-yl)-, (1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-
所属类别
生物化工：提取物物理化学性质
外观性状白色结晶性粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于紫菀。
熔点161-162°
比旋光度D26.5 -56.1° (c = 1.07 in chloroform)
沸点485.6±14.0 °C(Predicted)
密度0.941±0.06 g/cm3(Predicted)
溶解度Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
形态粉末
颜色White to off-white
LogP10.401 (est)
常见问题列表
药理活性
紫菀酮是从一种常见菊科植物—紫菀Aster tataricus L.f.的根及根茎中提取的。传统医学认为其性温，味苦、辛，润肺下气，具有消痰止咳之功效，常用于用于治疗痰多喘咳、新久咳嗽、劳嗽咳血之症。生物活性
Shionone 从 Aster tataricus 中分离，是一种三萜类化合物，具有镇咳，抗炎活性。 Shionone 具有独特的六元四环骨架和 3-氧代-4-单甲基结构。体内研究
Shionone (orally administration; 80 mg/kg; 3 days; once daily) shows the trend of enhancing sputum secreting, but has no effect on ammonia-induced cough and reduces xylene-induced ear edema.
| Animal Model: | ICR male mice |
| Dosage: | 80 mg/kg |
| Administration: | Orally administration; 3 days; once daily |
| Result: | Reduced the ear edema for 11.3% by use shionone. |