104869-31-0
104869-31-0 结构式
基本信息
英文别名
NF 023NF023 hexasodium
NF 023 hydrate
8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE)]BIS-(1,3,5-NAPHTHALENETRISULFONIC ACID), 6NA
8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt
8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid hexasodium salt
8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENECARBONYLIMINO)]BIS-1,3,5-NAPHTHALENE-TRISULPHONIC ACID, HEXASODIUM SALT
8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE CARBONYLIMINO)]BIS(1,3,5-NAPHTHALENE-TRISULFONIC ACID) HEXASODIUM SALT
8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate
8,8μ-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hydrate hexasodium salt
NF 023价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-108676 | NF 023 NF023 hexasodium | 104869-31-0 | 5mg | 2800元 |
| 2024/04/30 | HY-108676 | NF 023 NF023 hexasodium | 104869-31-0 | 10mg | 4500元 |
常见问题列表
生物活性
NF023 hexasodium 是具有选择性的、竞争性的 P2X1 受体拮抗剂，其对人 P2X1、P2X3、P2X2 和 P2X4 的 IC50 值分别为 0.21 μM、28.9 μM、> 50 μM 和> 100 μM。体外研究
NF023 is selective for recombinant Gi alpha-1 and recombinant Go alpha (EC
50
value of approximately 300 nM).
NF023 inhibits P2X1 receptors in a voltage-insensitive manner. NF023 (5 and 30 μM) causes a shift of the concentration-response curve to the right without affecting the maximal response to ATP (K
B
=1.190.2 μM).
体内研究
NF023 (100 µmol/kg i.v.) antagonizes vasopressor responses to α,β-mATP but not to noradrenaline In pithed rats.