1057677-92-5
英文名称
2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol
CAS
1057677-92-5
分子式
C27H29N5O
分子量
439.552
MOL 文件
1057677-92-5.mol
1057677-92-5 结构式
应用领域
用途一
LEQ506, also known as NPV-LEQ506, is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Smoothened antagonist LEQ506 selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway, thereby inhibiting tumor cell growth.