107429-63-0
107429-63-0 结构式
基本信息
中文别名
林托必利 英文别名
LintoprideBenzamide, 4-amino-5-chloro-N-[(1-ethyl-4,5-dihydro-1H-imidazol-2-yl)methyl]-2-methoxy-
物理化学性质
沸点494.1±45.0 °C(Predicted)
密度1.35±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)13.20±0.46(Predicted)
形态Solid
颜色Light yellow to yellow
常见问题列表
生物活性
Lintopride是 5HT4 拮抗剂，对5HT3 有轻微拮抗作用。靶点
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5-HT 4 Receptor
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5-HT 3 Receptor
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体外研究
Lintopride significantly increases the lower oesophageal sphincter basal tone without affecting lower oesophageal sphincter physiological relaxation after swallowing. Peristaltic waves are also enhanced by Lintopride.