112137-89-0
112137-89-0 结构式
基本信息
中文别名
米索前列醇酸米索前列醇酸[干冰运输]
米索前列醇酸,外消旋混合物
(11ALPHA,13E)-11,16-二羟基-16-甲基-9-氧代-前列腺-13-烯-1-酸
英文别名
MISOPROSTOL ACIDMISOPROSTOL FREE ACID
Misoprostol Acid USP/EP/BP
Misoprostol acid,racemic mixture
Misoprostol Acid, Technical Grade 65%
Misoprostol Acid (10 mg in 1 mL Methyl Acetate)
(-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E
(+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1
(+/-)-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E1
(11a,13E)-11,16-Dihydroxy-16-methyl-9-oxo-prost-13-en-1-oic Acid
所属类别
原料药：前列腺素类药物理化学性质
沸点538.3±50.0 °C(Predicted)
密度1.118±0.06 g/cm3(Predicted)
储存条件-20°C
溶解度Chloroform
酸度系数(pKa)4.77±0.10(Predicted)
形态黄色粘稠油状物。
颜色淡黄色
稳定性对温度敏感
常见问题列表
生物活性
Misoprostol acid 是一种 Misoprostol 的活性代谢物。Misoprostol 是前列腺素 E1 (PGE1) 的合成类似物，被广泛吸收，口服后迅速在胃肠道中转化成 Misoprostol acid。Misoprostol 可用于非甾体类抗炎药诱发的 (NSAID) 胃溃疡，还可用于引产的研究。靶点
Prostaglandin E1 (PGE1)
体内研究
Unlike the Misoprostol, Misoprostol acid is detectable in plasma. Misoprostol is a lipophilic methyl ester prodrug and is readily metabolized to the free acid, which is the biologically active form. Misoprostol is used worldwide for a variety of indications in obstetrics and gynecology. Misoprostol has both gastric antisecretory and mucosal protective effects.