115136-25-9
中文名称
Rabies Virus Glycoprotein
英文名称
Rabies Virus Glycoprotein
CAS
115136-25-9
分子式
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基本信息
中文别名
狂犬病病毒糖蛋白狂犬病病毒糖蛋白多肽
H-TYR-THR-ILE-TRP-MET-PRO-GLU-ASN-PRO-ARG-PRO-GLY-THR-PRO-CYS-ASP-ILE-PHE-THR-ASN-SER-ARG-GLY-LYS-ARG-ALA-SER-ASN-GLY-OH
英文别名
Rabies Virus Glycoprotein常见问题列表
生物活性
Rabies Virus Glycoprotein 是由 29 个氨基酸残基构成的细胞穿透肽，来源于狂犬病病毒糖蛋白，它能够穿过血脑屏障，进入脑细胞。体外研究
RVG peptide is successfully used to carry a variety of cargos into brain cells such as plasmids, siRNAs, proteins, and nanoparticles. RVG29 can govern the interaction of viral particles with at least three known receptors, including neural cell adhesion molecule (NCAM), the p75 neurotrophin receptor (P75NTR), and nicotinic acetylcholine receptors (NAChRs). The RVG29 peptide enhances the brain-specific function of a range of systemically delivered agents, particularly nucleic acids.