115534-33-3
中文名称
TMA-DPH(疏水膜荧光探针)
英文名称
TMA-DPH
CAS
115534-33-3
分子式
C28H31NO3S
分子量
461.62
MOL 文件
115534-33-3.mol
更新日期
2024/07/12 16:05:07
115534-33-3 结构式
基本信息
中文别名
膜电位荧光探针TMA-DPHTMA-DPH(疏水膜荧光探针)
英文别名
TMA-DPHTMA-DPH *CAS#: 115534-33-3*
4'-(Trimethylammonio)diphenylhexatrien
4'-(TRIMETHYLAMMONIO)DIPHENYLHEXATRIENE
1-(4-TRIMETHYLAMMONIUMPHENYL)-6-PHENYL-1 ,3,5-HEXAT
1,6-DIPHENYL-1,3,5-HEXATRIENE-4'-TRIMETHYLAMMONIUM TOSYLATE
4'-(Trimethylammonio)diphenylhexatriene p-toluenesulfonate
N,N,N-TRIMETHYL-4-[6-PHENYLHEXATRIEN-1-YL]PHENYLAMMONIUM TOSYLATE
1-(4-Trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene p-toluenesulfonate
1-(4-TRIMETHYLAMMONIUMPHENYL)-6-PHENYL-1,3,5-HEXATRIENE P-TOLUENESULFONATE
常见问题列表
生物活性
TMA-DPH 是一种疏水性荧光膜探针 (Ex=355 nm; Em=430 nm)。体外研究
In contact with cells, TMA-DPH is instantaneously incorporated into the plasma membrane. TMA-DPH is concentrated in lysosomes and highly acidic late endosomes. The TMA-DPH fluorescence lifetime remains constant, 6.2±0.2 ns, below the same critical concentration of 2 μM, but decreases significantly with higher concentrations. This decrease, however, slows down above 5 μM. The TMA-DPH fluorescence anisotropy displays a similar evolution to the fluorescence lifetime. It is first constant, 0.283±0.003, again until 2 μM, and then decreases rapidly to 0.270±0.003 with 5 μM, continuing to fall, but at a lower rate with higher concentrations.