115931-65-2
115931-65-2 结构式
基本信息
中文别名
化合物 T14977 英文别名
CL 275838Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 4,5-dihydro-4-[2-[4-(phenylmethyl)-1-piperazinyl]acetyl]-7-[3-(trifluoromethyl)phenyl]-
物理化学性质
沸点636.7±55.0 °C(Predicted)
密度1.33±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)6.62±0.10(Predicted)
常见问题列表
生物活性
CL-275838 是一种记忆力提高剂，同时也是一种抗抑郁剂。体内研究
CL 275,838 metabolism has sex-dependent differences in rat. CL 275,838 does not appreciably affect its own oxidation or cause significant hepatic microsomal enzyme induction in the male or female rat, except for slight enhancement of some components of the P450 system at doses (300 mg/kg once daily for 7 days) well above the effective pharmacological range.