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1177356-70-5

中文名称 (+)-Blebbistatin
英文名称 (+)-Blebbistatin
CAS 1177356-70-5
分子式 C18H16N2O2
分子量 292.33
MOL 文件 1177356-70-5.mol
更新日期 2024/08/06 14:59:09
1177356-70-5 结构式 1177356-70-5 结构式

基本信息

中文别名
(+)-BLEBBISTATIN
英文别名
(+)Blebbistatin,(+) Blebbistatin
(+)-Blebbistatin - CAS 1177356-70-5 - Calbiochem
4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aR)-

物理化学性质

储存条件-20C
溶解度DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 12.5 mg/ml
形态黄色固体

应用领域

用途1

Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. It blocks both blebbing and cytokinesis at 50-100μM. A negative control for the (S)-(-)-Blebblastatin. [a]D= +110 (c= 1.21 CHCl3) (-)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-on e

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