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119171-73-2

中文名称 10-乙酰基-3,7-二羟基吩嗪
英文名称 10-ACETYL-3,7-DIHYDROXYPHENOXAZINE
CAS 119171-73-2
分子式 C14H11NO4
分子量 257.24
MOL 文件 119171-73-2.mol
更新日期 2024/12/31 10:23:46
119171-73-2 结构式 119171-73-2 结构式

基本信息

中文别名
荧光红染料
7-二羟基吩噁嗪
10-乙酰基-3
10-乙酰基-3,7-二羟基吩嗪
10-乙酰基-3,7-二羟基吩噁嗪
10-乙酰基-3,7-二羟基吩嗪,刃天青红
荧光底物-10-乙酰基-3,7-二羟基吩嗪
刃天青红, 10-乙酰基-3,7-二羟基吩嗪
1-(3,7-二羟基-10H-吩恶嗪-10-基)乙酮
过氧化氢荧光探针(ADHP),AMPLIFLU RED
英文别名
ADHP
AMPLEX RED
AMPLIFLU RED
Amplisyn Red, 99%
AMPLEX(R) RED REAGENT
10-Acetyl-3,7-dihydroxypenoxazin
10-ACETYL-3,7-DIHYDROXYPHENOXAZINE
10-ACETYL-3,7-DIHYDROXYPHENOXAZINE,99%
10-ACETYL-3,7-DIHYDROXYPHENOXAZINE [ADHP]
ADHP [10-Acetyl-3,7-dihydroxyphenoxazine]
所属类别
生物化工:荧光成像

物理化学性质

熔点>250 °C (decomp)
沸点618.6±55.0 °C(Predicted)
密度1.459±0.06 g/cm3(Predicted)
储存条件2-8°C
溶解度DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2)1:5: 0.15 mg/ml; Ethanol: 1.5 mg/ml
酸度系数(pKa)9.41±0.20(Predicted)
形态结晶固体
颜色Light brown to brown

安全数据

危险性符号(GHS)GHS hazard pictograms
GHS07
警示词警告
危险性描述H302
危险品标志Xn
危险类别码22
WGK Germany3

常见问题列表

生物活性
ADHP 是一种荧光过氧化物酶底物(λex=530 nm, λem=590 nm)。
体外研究

To obtain the parameters K m and k cat for Compound I, two independent methods are used. Initially, the oxidation of ADHP using the injector functionality built-in to the fluorescence plate reader is studied. The auto-injector dispenses the H 2 O 2 to initiate the reaction, as a means of generating a set of progress curves. Analysis for MPO-mediated oxidation of ADHP gives a K m of 31±4 μM and the k cat of 186± 6 s −1 .The k obs also increases over the experimental range of ADHP concentrations from 1 to 80 μM and for the converse experiment holding substrate constant over 3 to 45 nM MPO. The apparent second order rate constant obtain from the slope of k obs against ADHP concentration K app on is 2.1±0.2 mM/s.

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