1246960-27-9
中文名称
依格列汀
英文名称
Evogliptin hydrochloride
CAS
1246960-27-9
分子式
C19H27ClF3N3O3
分子量
437.89
MOL 文件
1246960-27-9.mol
1246960-27-9 结构式
应用领域
用途一
Evogliptin, also known as DA-1229, is a potent and selective DPP4 inhibitor (dipeptidyl peptidase 4 inhibitor). Evogliptin improves insulin resistance and delays the onset of diabetes. Evogliptin improves the insulin sensitivity in HF mice and delays the onset of diabetes in young db/db mice. DA-1229 monotherapy (5 mg for 12 weeks) improved HbA1c, fasting plasma glucose level, OGTT results and β-cell function. This drug was well tolerated in Korean subjects with type 2 diabetes mellitus.