1253643-88-7
中文名称
DiAzKs
英文名称
DiAzKs
CAS
1253643-88-7
分子式
C11H20N4O4
分子量
272.3
MOL 文件
1253643-88-7.mol
更新日期
2023/06/09 11:23:34
1253643-88-7 结构式
基本信息
中文别名
ABK 试剂交联 - 氨基酸/ DIAZK
N6-((2-(3-甲基-3H-重氮化合物-3-基)乙氧基)羰基)-L-赖氨酸
英文别名
DiAzKsH-L-Photo-lysine
Cross-Linking-Amino-Acid / DiAzK
N6-[[2-(3-Methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine
物理化学性质
密度1.39±0.1 g/cm3(Predicted)
溶解度Soluble to 10 mM in water with gentle warming and to 100 mM in 1eq. HCl
酸度系数(pKa)2.53±0.24(Predicted)
形态Solid
颜色White to yellow
常见问题列表
生物活性
H-L-Photo-lysine 是一种含有重氮基的赖氨酸氨基酸，也是一种光交联剂。H-L-Photo-lysine 可以选择性的插入到蛋白质中，并用于在体外和活细胞中交联蛋白质-蛋白质相互作用。H-L-Photo-lysine 用作紫外光激活的光交联探针。体外研究
Photo-lysine, which is readily incorporated into proteins by native mammalian translation machinery, can be used to capture and identify proteins that recognize lysine post-translational modifications (PTMs), including 'readers' and 'erasers' of histone modifications.