1261728-71-5
中文名称
7-(二氟甲基)喹啉
英文名称
7-(Difluoromethyl)Quinoline
CAS
1261728-71-5
分子式
C10H7F2N
分子量
179.17
MOL 文件
1261728-71-5.mol
更新日期
2024/09/25 10:00:18
1261728-71-5 结构式
基本信息
中文别名
7-(二氟甲基)喹啉 英文别名
7-(Difluoromethyl)QuinolineQuinoline, 7-(difluoromethyl)-
7-(Difluoromethyl)Quinoline(WXC01613)
应用领域
用途一
7-(Difluoromethyl)quinoline is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.