1309371-03-6
中文名称
2-TrifluoroMethyl-2'-Methoxychalcone
英文名称
2-TrifluoroMethyl-2'-Methoxychalcone
CAS
1309371-03-6
分子式
C17H13F3O2
分子量
306.28
MOL 文件
1309371-03-6.mol
1309371-03-6 结构式
基本信息
中文别名
2-三氟甲基-2'-甲氧基查尔酮 英文别名
2-TrifluoroMethyl-2'-Methoxychalcone2-Propen-1-one, 1-(2-methoxyphenyl)-3-[2-(trifluoromethyl)phenyl]-, (2E)-
物理化学性质
沸点395.6±42.0 °C(Predicted)
密度1.238±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度≤11mg/ml in ethanol;5mg/ml in DMSO;14mg/ml in dimethyl formamide
形态solution in acetate.
应用领域
用途1
2-Trifluoromethyl-2'-methoxychalcone is a novel chalcone derivative as potent Nrf2 activators in mice and human lung epithelial cells. 2-Trifluoromethyl-2'-methoxychalcone is a potent activator of Nr f2, both, in vitro and in mice. 4 Human bronchial epithelial cells treated with 10 μM 2-trifluoromethyl-2'-methoxychalcone showed a marked increase in the expression of the Nrf2-regulated antioxidant genes, GCLM and NQO1.