13312-52-2
13312-52-2 结构式
基本信息
中文别名
(9Z)-Β-胡萝卜素 英文别名
(9Z)-β-CaroteneNeo-β-carotene U
neo U-β-Carotene
9-cis-β-Carotene
(9Z)-β,β-Carotene
(9Z)-beta-Carotene
物理化学性质
沸点654.7±22.0 °C(Predicted)
密度0.941±0.06 g/cm3(Predicted)
储存条件-20°C
形态Solid
颜色Light brown to brown
BRN3227021
常见问题列表
生物活性
9-cis-β-Carotene 一种视网膜的前体 (precursor)，由 β-胡萝卜素加氧酶 1 (BCMO1) 裂解产生 9-cis-retinal。9-cis-β-Carotene 在动物模型中抑制视网膜光感受器变性和帮助恢复视网膜功能。9-cis-β-Carotene 有潜力用于先天性静止夜盲症的研究。体外研究
9-cis-β-Carotene (1 μM; 18 hours) formulates with the Miglyol 810 and the“antioxidant mix” is incubated to eye cups. The eye cups are isolated from the neuro-retina attached to the underlying RPE tissue from RPE65rd12 mouse. It prevents S- and M-cones degeneration and leads to over 2- and 9- fold higher m-opsin and s-opsin positive staining compares to the control group.
体内研究
In a mouse model of retinoid cycle defect, RPE65rd12. Mice with an extract of Dunaliella Bardawil algae rich in 9-cis-β-Carotene (9CBC) rescues retinal function and preserves cone structure by oral administration.