1350456-56-2
中文名称
FMOC-VAL-CIT-PAB-MMAE
英文名称
FMoc-Val-Cit-PAB-MMAE
CAS
1350456-56-2
分子式
C73H104N10O14
分子量
1345.67
MOL 文件
1350456-56-2.mol
更新日期
2024/09/04 11:32:32
1350456-56-2 结构式
基本信息
中文别名
化合物FMOC-VAL-CIT-PAB-MMAE 英文别名
Fmoc-VC-PAB-MMAEFMoc-Val-Cit-PAB-MMAE
Fmoc-Val-Cit-PABC-MMAE
L-Valinamide, N-[[[4-[[N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-meth...
N-[[[4-[[N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide
所属类别
生物化工：激动剂抑制剂物理化学性质
沸点1353.5±65.0 °C(Predicted)
密度1.198±0.06 g/cm3(Predicted)
酸度系数(pKa)10.63±0.46(Predicted)
形态Solid
颜色White to off-white
应用领域
用途一
Fmoc-Val-Cit-PAB-MMAE is a precursor of antibody drug conjugate containing a cleavable Val-Cit peptide, a PABC linker and a MMAE payload. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells.