1355446-05-7

英文名称 ML309

CAS 1355446-05-7

分子式 C29H29FN4O2

分子量 484.56

MOL 文件 1355446-05-7.mol

1355446-05-7 结构式

基本信息应用领域

基本信息

英文别名

ML309

应用领域

用途一

ML309 is a potent inhibitor of R132H mutant IDH1 capable of reducing 2-hydroxyglutarate production in U87 MG glioblastoma cells. ML309 is capable of potent and selective inhibition of mutant IDH1 and effectively lowers cell-based production of 2-HG in a U87MG mutant glioblastoma cell line.