1374507-23-9
中文名称
CO-1686中间体3
英文名称
tert-butyl (3-((2-chloro-5-(trifluoroMethyl)pyriMidin-4-yl)aMino)phenyl)carbaMate
CAS
1374507-23-9
分子式
C16H16ClF3N4O2
分子量
388.77
MOL 文件
1374507-23-9.mol
更新日期
2024/03/08 11:55:43
1374507-23-9 结构式
基本信息
中文别名
CO-1686中间体CO-1686中间体3
CO-1686 中间体一
ROCILETINIB中间体
C0-1686 中间体N-3
N-[3-[[2-氯-5-(三氟甲基)-4-嘧啶基]氨基]苯基]氨基甲酸叔丁酯
英文别名
ROCI-003CO1686 Intermediate2
CO-1686 intermediate 3
N-[3-[[2-Chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phen...
tert-butyl (3-((2-chloro-5-(trifluoroMethyl)pyriMidin-4-yl)aMino)phenyl)carbaMate
tert-butyl N-(3-{[2-chloro-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)carbamate
N-[3-[[2-Chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]carbamic acid 1,1-dimethylethyl ester
Carbamic acid, N-[3-[[2-chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-, 1,1-dimethylethyl ester
物理化学性质
沸点446.2±45.0 °C(Predicted)
密度1.406±0.06 g/cm3(Predicted)
酸度系数(pKa)13.43±0.70(Predicted)
InChIInChI=1S/C16H16ClF3N4O2/c1-15(2,3)26-14(25)23-10-6-4-5-9(7-10)22-12-11(16(18,19)20)8-21-13(17)24-12/h4-8H,1-3H3,(H,23,25)(H,21,22,24)
InChIKeyLEKSPBMQHCLAEB-UHFFFAOYSA-N
SMILESC(OC(C)(C)C)(=O)NC1=CC=CC(NC2C(C(F)(F)F)=CN=C(Cl)N=2)=C1