1391063-17-4
中文名称
博舒替尼杂质
英文名称
Bosutinib Impurity 5
CAS
1391063-17-4
分子式
C26H29Cl2N5O3
分子量
530.45
MOL 文件
1391063-17-4.mol
更新日期
2024/08/19 13:58:19
![1391063-17-4 结构式](/CAS/20180808/GIF/1391063-17-4.gif)
基本信息
中文别名
博舒替尼异构体伯舒替尼杂质5
波舒替尼异构体1
化合物 T28374
英文别名
Bosutinib isomer 1Bosutinib Isomer I
Bosutinib Isomer I (PF-06651481-00)
3-Quinolinecarbonitrile, 4-[(3,5-dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-
所属类别
分析化学:药典标准品和杂质标准品物理化学性质
溶解度可溶于氯仿(轻微)、DMSO(轻微)、甲醇(轻微、加热)
形态固体
颜色白色至浅棕色
稳定性Stable under recommended storage conditions., Stable Under Recommended Storage C
应用领域
用途一
Kinase inhibitors, such as?bosutinib,?are useful cancer drugs but their target specificity is not fully understood. 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile has been employed as a clinical kinase inhibitor bosutinib to elucidate the recognition mechanism between the ATP-binding site and the compound.