141807-57-0
141807-57-0 结构式
基本信息
英文别名
RTI-113RTI 4229-113
(1R,2S,3S,5S)-3-(4-Chlorophenyl)-8-Methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Phenyl Ester Hydrochloride
[1R-(exo,exo)]-3-(4-Chlorophenyl)-8-Methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Phenyl Ester Hydrochloride
应用领域
用途一
RTI-113 is a 3-phenyltropane analogue that acts as a potent and selective dopamine uptake inhibitor. RTI-113 has been shown to reduce cocaine self-administration at high occupancy of dopamine transporter. Studies suggest that RTI-113 and its analogs may be useful tools for developing potential agonist therapies for cocaine dependence.