1422423-23-1

中文名称 EMICORON

英文名称 EMICORON

CAS 1422423-23-1

分子式 C52H58N6O4

分子量 831.055

MOL 文件 1422423-23-1.mol

1422423-23-1 结构式

基本信息应用领域

基本信息

中文别名

化合物 T27258

英文别名

EMICORON
Pyreno[2,1,10-def:7,8,9-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetrone, 13-(1-pieridinyl)-2,5,9-tris[2-(1-pieridinyl)ethyl]-

应用领域

用途一

Emicoron is a multi-targeting G4 ligand. Emicoron showed Strong Antitumor Efficacy against Advanced Models of Human Colon Cancer. EMICORON showed a marked therapeutic efficacy, as it inhibited the growth of patient-derived xenografts (PDX) and orthotopic colon cancer and strongly reduced the dissemination of tumor cells to lymph nodes, intestine, stomach, and liver. EMICORON had an unprecedented antitumor activity warranting further studies of EMICORON-based combination treatments.